The mitogen-activated protein (MAP) kinase ERK induces tRNA synthesis by phosphorylating TFIIIB
RNA polymerase (pol) III transcription increases within minutes of serum addition to growth-arrested fibroblasts. We show that ERK mitogen-activated protein kinases regulate pol III output by directly binding and phosphorylating the BRF1 subunit of transcription factor TFIIIB. Blocking the ERK signa...
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| Vydáno v: | EMBO J |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2003
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC155998/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12743036/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg240 |
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