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The mitogen-activated protein (MAP) kinase ERK induces tRNA synthesis by phosphorylating TFIIIB
RNA polymerase (pol) III transcription increases within minutes of serum addition to growth-arrested fibroblasts. We show that ERK mitogen-activated protein kinases regulate pol III output by directly binding and phosphorylating the BRF1 subunit of transcription factor TFIIIB. Blocking the ERK signa...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2003
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC155998/ https://ncbi.nlm.nih.gov/pubmed/12743036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg240 |
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