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DNA Damage and L1 Retrotransposition

Barbara McClintock was the first to suggest that transposons are a source of genome instability and that genotoxic stress assisted in their mobilization. The generation of double-stranded DNA breaks (DSBs) is a severe form of genotoxic stress that threatens the integrity of the genome, activates cel...

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Autors principals: Farkash, Evan A., Prak, Eline T. Luning
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1559917/
https://ncbi.nlm.nih.gov/pubmed/16877815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/JBB/2006/37285
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