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Gamma radiation increases endonuclease-dependent L1 retrotransposition in a cultured cell assay

Long Interspersed Elements (LINE-1s, L1s) are the most active mobile elements in the human genome and account for a significant fraction of its mass. The propagation of L1 in the human genome requires disruption and repair of DNA at the site of integration. As Barbara McClintock first hypothesized,...

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Autors principals: Farkash, Evan A., Kao, Gary D., Horman, Shane R., Prak, Eline T. Luning
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1385994/
https://ncbi.nlm.nih.gov/pubmed/16507671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkj522
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