Selection strength and hitchhiking around two anti-malarial resistance genes

Neutral mutations may hitchhike to high frequency when they are situated close to sites under positive selection, generating local reductions in genetic diversity. This process is thought to be an important determinant of levels of genomic variation in natural populations. The size of genome regions...

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Main Authors: Nash, Denae, Nair, Shalini, Mayxay, Mayfong, Newton, Paul N, Guthmann, Jean-Paul, Nosten, François, Anderson, Tim J.C
Format: Artigo
Jezik:Inglês
Izdano: The Royal Society 2005
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1559806/
https://ncbi.nlm.nih.gov/pubmed/16024377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2004.3026
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