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The role of hydrophobic interactions in initiation and propagation of protein folding

Globular proteins fold by minimizing the nonpolar surface that is exposed to water, while simultaneously providing hydrogen-bonding interactions for buried backbone groups, usually in the form of secondary structures such as α-helices, β-sheets, and tight turns. A primary thermodynamic driving force...

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Autori principali: Dyson, H. Jane, Wright, Peter E., Scheraga, Harold A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1559752/
https://ncbi.nlm.nih.gov/pubmed/16916929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605504103
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