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RAD18-independent ubiquitination of proliferating-cell nuclear antigen in the avian cell line DT40
Ubiquitination of proliferating-cell nuclear antigen (PCNA) at K164 by RAD6/RAD18 has a key role in DNA damage tolerance in yeast. Here, we report on the first genetic study of this modification in a vertebrate cell. As in yeast, mutation of K164 of PCNA to arginine in the avian cell line DT40 resul...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1559672/ https://ncbi.nlm.nih.gov/pubmed/16888649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400777 |
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