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Double-strand breaks arising by replication through a nick are repaired by cohesin-dependent sister-chromatid exchange

Molecular studies on double-strand break (DSB) repair in mitosis are usually performed with enzymatically induced DSBs, but spontaneous DSBs might arise because of replication failures, for example when replication encounters nicks. To study repair of replication-born DSBs, we defined a system in Sa...

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Hlavní autoři: Cortés-Ledesma, Felipe, Aguilera, Andrés
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1559660/
https://ncbi.nlm.nih.gov/pubmed/16888651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400774
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