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The glucocorticoid RU24858 does not distinguish between transrepression and transactivation in primary human eosinophils
BACKGROUND: Glucocorticoids are used to treat chronic inflammatory diseases such as asthma. Induction of eosinophil apoptosis is considered to be one of the main mechanisms behind the anti-asthmatic effect of glucocorticoids. Glucocorticoid binding to its receptor (GR) can have a dual effect on gene...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1559619/ https://ncbi.nlm.nih.gov/pubmed/16834783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-9255-3-10 |
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