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TIMP-3 inhibits the procollagen N-proteinase ADAMTS-2
ADAMTS-2 is an extracellular metalloproteinase responsible for cleaving the N-propeptides of procollagens I–III; an activity necessary for the formation of collagenous ECM (extracellular matrix). The four TIMPs (tissue inhibitors of metalloproteinases) regulate the activities of matrix metalloprotei...
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Hauptverfasser: | , , , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
Portland Press Ltd.
2006
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1559475/ https://ncbi.nlm.nih.gov/pubmed/16771712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060630 |
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