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Inhibition of hepatocyte nuclear factor 4 transcriptional activity by the nuclear factor κB pathway

HNF-4 (hepatocyte nuclear factor 4) is a key regulator of liver-specific gene expression in mammals. We have shown previously that the activity of the human APOC3 (apolipoprotein C-III) promoter is positively regulated by the anti-inflammatory cytokine TGFβ (transforming growth factor β) and its eff...

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Detalhes bibliográficos
Main Authors: Nikolaidou-Neokosmidou, Varvara, Zannis, Vassilis I., Kardassis, Dimitris
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1559460/
https://ncbi.nlm.nih.gov/pubmed/16771709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060169
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