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Mechanism of a Transcriptional Cross Talk between Transforming Growth Factor-β–regulated Smad3 and Smad4 Proteins and Orphan Nuclear Receptor Hepatocyte Nuclear Factor-4

We have shown previously that the transforming growth factor-β (TGFβ)-regulated Sma-Mad (Smad) protein 3 and Smad4 proteins transactivate the apolipoprotein C-III promoter in hepatic cells via a hormone response element that binds the nuclear receptor hepatocyte nuclear factor 4 (HNF-4). In the pres...

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Detalhes bibliográficos
Main Authors: Chou, Wan-Chih, Prokova, Vassiliki, Shiraishi, Keiko, Valcourt, Ulrich, Moustakas, Aristidis, Hadzopoulou-Cladaras, Margarita, Zannis, Vassilis I., Kardassis, Dimitris
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC151596/
https://ncbi.nlm.nih.gov/pubmed/12631740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-07-0375
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