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Characterization of Ca(2+) interactions with matrix metallopeptidase-12: implications for matrix metallopeptidase regulation
Matrix metallopeptidase-12 (MMP-12) binds three calcium ions and a zinc ion, in addition to the catalytic zinc ion. These ions are thought to have a structural role, stabilizing the active conformation of the enzyme. To characterize the importance of Ca(2+) binding for MMP-12 activity and the proper...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Portland Press Ltd.
2006
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1559459/ https://ncbi.nlm.nih.gov/pubmed/16737445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051933 |
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