Ca(2+)-dependent interaction between FKBP12 and calcineurin regulates activity of the Ca(2+) release channel in skeletal muscle.

Calcineurin is a Ca(2+) and calmodulin-dependent protein phosphatase with diverse cellular functions. Here we examined the physical and functional interactions between calcineurin and ryanodine receptor (RyR) in a C2C12 cell line derived from mouse skeletal muscle. Coimmunoprecipitation experiments...

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Detalhes bibliográficos
Main Authors: Shin, Dong Wook, Pan, Zui, Bandyopadhyay, Arun, Bhat, Manjunatha B, Kim, Do Han, Ma, Jianjie
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302340/
https://ncbi.nlm.nih.gov/pubmed/12414688
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