Mechanism of Action of 4-Phenoxyphenoxyethyl Thiocyanate (WC-9) against Trypanosoma cruzi, the Causative Agent of Chagas’ Disease

We investigated the molecular basis of the activity of 4-phenoxyphenoxyethyl thiocyanate (WC-9) against Trypanosoma cruzi, the etiological agent of Chagas’ disease. We found that growth inhibition of T. cruzi epimastigotes induced by this compound was associated with a reduction in the content of th...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Urbina, Julio A., Concepcion, Juan Luis, Montalvetti, Andrea, Rodriguez, Juan B., Docampo, Roberto
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2003
Sujets:	Mechanisms of Action: Physiological Effects
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC155860/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12760897/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.6.2047-2050.2003
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