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Mechanism of Action of 4-Phenoxyphenoxyethyl Thiocyanate (WC-9) against Trypanosoma cruzi, the Causative Agent of Chagas’ Disease

We investigated the molecular basis of the activity of 4-phenoxyphenoxyethyl thiocyanate (WC-9) against Trypanosoma cruzi, the etiological agent of Chagas’ disease. We found that growth inhibition of T. cruzi epimastigotes induced by this compound was associated with a reduction in the content of th...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Urbina, Julio A., Concepcion, Juan Luis, Montalvetti, Andrea, Rodriguez, Juan B., Docampo, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC155860/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12760897/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.6.2047-2050.2003
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