Characterization of Brucella abortus O-Polysaccharide and Core Lipopolysaccharide Mutants and Demonstration that a Complete Core Is Required for Rough Vaccines To Be Efficient against Brucella abortus and Brucella ovis in the Mouse Model

Brucella abortus rough lipopolysaccharide (LPS) mutants were obtained by transposon insertion into two wbk genes (wbkA [putative glycosyltransferase; formerly rfbU] and per [perosamine synthetase]), into manB (pmm [phosphomannomutase; formerly rfbK]), and into an unassigned gene. Consistent with gen...

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Autors principals: Monreal, D., Grilló, M. J., González, D., Marín, C. M., De Miguel, M. J., López-Goñi, I., Blasco, J. M., Cloeckaert, A, Moriyón, I.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2003
Matèries:
Microbial Immunity and Vaccines
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC155776/
https://ncbi.nlm.nih.gov/pubmed/12761107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.6.3261-3271.2003
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