Characterization of Brucella abortus O-Polysaccharide and Core Lipopolysaccharide Mutants and Demonstration that a Complete Core Is Required for Rough Vaccines To Be Efficient against Brucella abortus and Brucella ovis in the Mouse Model

Brucella abortus rough lipopolysaccharide (LPS) mutants were obtained by transposon insertion into two wbk genes (wbkA [putative glycosyltransferase; formerly rfbU] and per [perosamine synthetase]), into manB (pmm [phosphomannomutase; formerly rfbK]), and into an unassigned gene. Consistent with gen...

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Bibliographic Details
Main Authors: Monreal, D., Grilló, M. J., González, D., Marín, C. M., De Miguel, M. J., López-Goñi, I., Blasco, J. M., Cloeckaert, A, Moriyón, I.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2003
Subjects:
Microbial Immunity and Vaccines
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC155776/
https://ncbi.nlm.nih.gov/pubmed/12761107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.6.3261-3271.2003
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