Stx2-Specific Human Monoclonal Antibodies Protect Mice against Lethal Infection with Escherichia coli Expressing Stx2 Variants

Shiga toxin-producing Escherichia coli (STEC) strains are responsible for causing hemolytic-uremic syndrome (HUS), and systemic administration of Shiga toxin (Stx)-specific human monoclonal antibodies (HuMAbs) is considered a promising approach for prevention or treatment of the disease in children....

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Autors principals: Sheoran, Abhineet S., Chapman, Susan, Singh, Pradeep, Donohue-Rolfe, Arthur, Tzipori, Saul
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Microbial Immunity and Vaccines
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC155773/
https://ncbi.nlm.nih.gov/pubmed/12761090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.6.3125-3130.2003
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