Stx2-Specific Human Monoclonal Antibodies Protect Mice against Lethal Infection with Escherichia coli Expressing Stx2 Variants

Shiga toxin-producing Escherichia coli (STEC) strains are responsible for causing hemolytic-uremic syndrome (HUS), and systemic administration of Shiga toxin (Stx)-specific human monoclonal antibodies (HuMAbs) is considered a promising approach for prevention or treatment of the disease in children....

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Pubblicato in:	Infect Immun
Autori principali:	Sheoran, Abhineet S., Chapman, Susan, Singh, Pradeep, Donohue-Rolfe, Arthur, Tzipori, Saul
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2003
Soggetti:	Microbial Immunity and Vaccines
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC155773/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12761090/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.6.3125-3130.2003
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