Salt restriction induces pseudohypoaldosteronism type 1 in mice expressing low levels of the β-subunit of the amiloride-sensitive epithelial sodium channel

The amiloride-sensitive epithelial sodium channel (ENaC) is a heteromultimer of three homologous subunits (α-, β-, and γ-subunits). To study the role of the β-subunit in vivo, we analyzed mice in which the βENaC gene locus was disrupted. These mice showed low levels of βENaC mRNA expression in kidne...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Pradervand, Sylvain, Barker, Pierre M., Wang, Qing, Ernst, Stephen A., Beermann, Friedrich, Grubb, Barbara R., Burnier, Michel, Schmidt, Andrea, Bindels, Rene J. M., Gatzy, John T., Rossier, Bernard C., Hummler, Edith
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC15577/
https://ncbi.nlm.nih.gov/pubmed/9990093
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados