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Type 1 sphingosine 1-phosphate G protein-coupled receptor signaling of lymphocyte functions requires sulfation of its extracellular amino-terminal tyrosines

The type 1 sphingosine 1-phosphate (S1P) G protein-coupled receptor (S1P(1)) transduces signals from S1P that mediate thymocyte emigration, T cell transmigration of lymph nodes, and T cell chemotaxis in tissues. Alterations in expression of functional S1P(1) receptors by lymphocytes are the major me...

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Detalhes bibliográficos
Main Authors: Fieger, Claudia B., Huang, Mei-Chuan, Van Brocklyn, James R., Goetzl, Edward J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1557661/
https://ncbi.nlm.nih.gov/pubmed/16148028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.05-4476fje
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