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Sphingosine 1-Phosphate and Its G Protein-Coupled Receptors Constitute a Multifunctional Immunoregulatory System

The lysophospholipid growth factors sphingosine 1-phosphate (S1P) and lysophosphatidic acid (LPA) are generated by many cells involved in immunity, including macrophages, dendritic cells, mast cells, and platelets, with resultant lymph and plasma concentrations of 0.1–1 μM. All immune cells express...

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Bibliografske podrobnosti
Main Authors: Goetzl, Edward J., Wang, Wengang, McGiffert, Christine, Huang, Mei-Chuan, Gräler, Markus H.
Format: Artigo
Jezik:Inglês
Izdano: 2004
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1557660/
https://ncbi.nlm.nih.gov/pubmed/15258896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.20053
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