Vaccine-Induced Protection against Helicobacter pylori in Mice Lacking Both Antibodies and Interleukin-4

To test the hypothesis that a Th2 response to Helicobacter pylori is necessary for protection and to address the possibility that humoral and Th2 cellular responses may compensate for each other, we generated mice deficient in both interleukin-4 (IL-4) and antibodies. The immunized double-knockout m...

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Detalhes bibliográficos
Main Authors: Garhart, Christine A., Nedrud, John G., Heinzel, Frederick P., Sigmund, Norma E., Czinn, Steven J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC155749/
https://ncbi.nlm.nih.gov/pubmed/12761151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.6.3628-3633.2003
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