Vaccine-Induced Protection against Helicobacter pylori in Mice Lacking Both Antibodies and Interleukin-4

To test the hypothesis that a Th2 response to Helicobacter pylori is necessary for protection and to address the possibility that humoral and Th2 cellular responses may compensate for each other, we generated mice deficient in both interleukin-4 (IL-4) and antibodies. The immunized double-knockout m...

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Main Authors: Garhart, Christine A., Nedrud, John G., Heinzel, Frederick P., Sigmund, Norma E., Czinn, Steven J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2003
Teme:
Microbial Immunity and Vaccines
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC155749/
https://ncbi.nlm.nih.gov/pubmed/12761151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.6.3628-3633.2003
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