Mutation of luxS of Streptococcus pneumoniae Affects Virulence in a Mouse Model

The LuxS protein is required for the biosynthesis of the type 2 autoinducer (AI-2), which is involved in quorum sensing in a wide range of bacterial species. We have determined the effects of a defined luxS mutation on the virulence of Streptococcus pneumoniae. Although the luxS mutant displayed red...

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Pubblicato in:	Infect Immun
Autori principali:	Stroeher, Uwe H., Paton, Adrienne W., Ogunniyi, A. David, Paton, James C.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2003
Soggetti:	Molecular Pathogenesis
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC155746/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12761100/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.6.3206-3212.2003
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