Inhibition of Interleukin-17 Prevents the Development of Arthritis in Vaccinated Mice Challenged with Borrelia burgdorferi

We showed that Borrelia burgdorferi-vaccinated interferon gamma-deficient (IFN-γ(0)) mice challenged with the Lyme spirochete developed a prominent chronic severe destructive osteoarthropathy. The immune response underlying the development of the severe destructive arthritis involves interleukin-17...

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Detalhes bibliográficos
Main Authors: Burchill, Matthew A., Nardelli, Dean T., England, Douglas M., DeCoster, David J., Christopherson, John A., Callister, Steven M., Schell, Ronald F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC155727/
https://ncbi.nlm.nih.gov/pubmed/12761128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.6.3437-3442.2003
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