Genetic Diversity and Antigenic Polymorphism in Plasmodium falciparum: Extensive Serological Cross-Reactivity between Allelic Variants of Merozoite Surface Protein 2

Diversity in the surface antigens of malaria parasites is generally assumed to be a mechanism for immune evasion, but there is little direct evidence that this leads to evasion of protective immunity. Here we show that alleles of the highly polymorphic merozoite surface protein 2 (MSP-2) can be grou...

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Auteurs principaux: Franks, Simon, Baton, Luke, Tetteh, Kevin, Tongren, Eric, Dewin, David, Akanmori, Bartholomew D., Koram, Kojo A., Ranford-Cartwright, Lisa, Riley, Eleanor M.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2003
Sujets:
Fungal and Parasitic Infections
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC155717/
https://ncbi.nlm.nih.gov/pubmed/12761133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.6.3485-3495.2003
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