Antibodies to Variant Antigens on the Surfaces of Infected Erythrocytes Are Associated with Protection from Malaria in Ghanaian Children

Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is a variant antigen expressed on the surface of infected erythrocytes. Each parasite genome contains about 40 PfEMP1 genes, but only 1 PfEMP1 gene is expressed at a given time. PfEMP1 serves as a parasite-sequestering ligand to endotheli...

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Autors principals: Dodoo, Daniel, Staalsoe, Trine, Giha, Haider, Kurtzhals, Jørgen A. L., Akanmori, Bartholomew D., Koram, Kojo, Dunyo, Samuel, Nkrumah, Francis K., Hviid, Lars, Theander, Thor G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Fungal and Parasitic Infections
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC98376/
https://ncbi.nlm.nih.gov/pubmed/11349035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.6.3713-3718.2001
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