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Inhibition of Transforming Growth Factor-β1–induced Signaling and Epithelial-to-Mesenchymal Transition by the Smad-binding Peptide Aptamer Trx-SARA
Overexpression of the inhibitory Smad, Smad7, is used frequently to implicate the Smad pathway in cellular responses to transforming growth factor β (TGF-β) signaling; however, Smad7 regulates several other proteins, including Cdc42, p38MAPK, and β-catenin. We report an alternative approach for more...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2006
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1556379/ https://ncbi.nlm.nih.gov/pubmed/16775010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-10-0990 |
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