Caricamento...

Mice reconstituted with DNA polymerase β-deficient fetal liver cells are able to mount a T cell-dependent immune response and mutate their Ig genes normally

The ubiquitously expressed, error-prone DNA polymerase β (polβ) plays a role in base excision repair, and the involvement of this molecule in the nonhomologous end joining (NHEJ) process of DNA repair has recently been demonstrated in yeast. Polβ-deficient mice are not viable, and studies on conditi...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Esposito, Gloria, Texido, Gemma, Betz, Ulrich A. K., Gu, Hua, Müller, Werner, Klein, Ulf, Rajewsky, Klaus
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2000
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC15557/
https://ncbi.nlm.nih.gov/pubmed/10655502
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !