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Autostimulatory effects of IL-6 on excessive B cell differentiation in patients with systemic lupus erythematosus: analysis of IL-6 production and IL-6R expression.

Introducing avidin-biotin complex ELISA for anti-DNA antibody, the mechanism of in vitro production of anti-ssDNA antibody as well as of polyclonal immunoglobulin mediated by an IL-6-IL-6R loop was studied in patients with systemic lupus erythematosus (SLE). Regardless of the presence or absence of...

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Autors principals: Kitani, A, Hara, M, Hirose, T, Harigai, M, Suzuki, K, Kawakami, M, Kawaguchi, Y, Hidaka, T, Kawagoe, M, Nakamura, H
Format: Artigo
Idioma:Inglês
Publicat: 1992
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1554365/
https://ncbi.nlm.nih.gov/pubmed/1563109
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