The sentrin-conjugating enzyme mUbc9 interacts with GLUT4 and GLUT1 glucose transporters and regulates transporter levels in skeletal muscle cells

Glucose transport in insulin-regulated tissues is mediated by the GLUT4 and GLUT1 transporters. Using the yeast two-hybrid system, we have cloned the sentrin-conjugating enzyme mUbc9 as a protein that interacts with the GLUT4 COOH-terminal intracellular domain. The mUbc9 enzyme was found to bind dir...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Giorgino, Francesco, de Robertis, Ottilia, Laviola, Luigi, Montrone, Carmela, Perrini, Sebastio, McCowen, Karen C., Smith, Robert J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15543/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10655495/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.3.1125
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