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Antigen binding and complement fixing activity of IgM molecules reassociated in the presence and absence of J chains

Monoclonal IgM with anti-Pr(2) activity was purified from the serum of a patient with chronic cold agglutinin disease. After reduction with 20 mM dithiothreitol IgM molecules and J chains were separated. The subunits were reoxidized in the presence and in the absence of J chains. In both mixtures co...

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Detalhes bibliográficos
Main Authors: Kownatzki, E., Drescher, M.
Formato: Artigo
Idioma:Inglês
Publicado em: 1973
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1553969/
https://ncbi.nlm.nih.gov/pubmed/4205038
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