Immunogenicity and in vitro protective efficacy of a recombinant multistage Plasmodium falciparum candidate vaccine

Compared with a single-stage antigen-based vaccine, a multistage and multivalent Plasmodium falciparum vaccine would be more efficacious by inducing “multiple layers” of immunity. We have constructed a synthetic gene that encodes for 12 B cell, 6 T cell proliferative, and 3 cytotoxic T lymphocyte ep...

Full description

Saved in:
Bibliographic Details
Main Authors: Shi, Ya Ping, Hasnain, Seyed E., Sacci, John B., Holloway, Brian P., Fujioka, Hisashi, Kumar, Nirbhay, Wohlhueter, Robert, Hoffman, Stephen L., Collins, William E., Lal, Altaf A.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 1999
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC15536/
https://ncbi.nlm.nih.gov/pubmed/9990073
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items