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Lupus-derived autoantibodies with dual autoactivity: anti-DNA and anti-Fc. I. Comparison of IgG autoreactivities with single-chain Fv derivatives.

Investigations into the intrinsic affinity and reactivity of autoanti-DNA active sites were initiated through the use of purified monoclonal IgG and the synthesis of single-chain Fv derivatives of murine monoclonal anti-DNA autoantibodies BV 04-01 and BV 17-45. Results showed that relative to the re...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rumbley, C A, Voss, E W
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1995
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1553421/
https://ncbi.nlm.nih.gov/pubmed/7586688
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