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A 5′ RNA element promotes dengue virus RNA synthesis on a circular genome

The mechanisms of RNA replication of plus-strand RNA viruses are still unclear. Here, we identified the first promoter element for RNA synthesis described in a flavivirus. Using dengue virus as a model, we found that the viral RdRp discriminates the viral RNA by specific recognition of a 5′ element...

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Detalhes bibliográficos
Main Authors: Filomatori, Claudia V., Lodeiro, Maria F., Alvarez, Diego E., Samsa, Marcelo M., Pietrasanta, Lía, Gamarnik, Andrea V.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1553207/
https://ncbi.nlm.nih.gov/pubmed/16882970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1444206
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