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Mutation in the U2 snRNA influences exon interactions of U5 snRNA loop 1 during pre-mRNA splicing
The U2 and U6 snRNAs contribute to the catalysis of intron removal while U5 snRNA loop 1 holds the exons for ligation during pre-mRNA splicing. It is unclear how different exons are positioned precisely with U5 loop 1. Here, we investigate the role of U2 and U6 in positioning the exons with U5 loop...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1553196/ https://ncbi.nlm.nih.gov/pubmed/16888626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601258 |
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