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The U1, U2 and U5 snRNAs crosslink to the 5′ exon during yeast pre-mRNA splicing

Activation of pre-messenger RNA (pre-mRNA) splicing requires 5′ splice site recognition by U1 small nuclear RNA (snRNA), which is replaced by U5 and U6 snRNA. Here we use crosslinking to investigate snRNA interactions with the 5′ exon adjacent to the 5′ splice site, prior to the first step of splici...

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Detalhes bibliográficos
Main Authors: McGrail, Joanne C., O’Keefe, Raymond T.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2241886/
https://ncbi.nlm.nih.gov/pubmed/18084028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm1098
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