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The U1, U2 and U5 snRNAs crosslink to the 5′ exon during yeast pre-mRNA splicing

Activation of pre-messenger RNA (pre-mRNA) splicing requires 5′ splice site recognition by U1 small nuclear RNA (snRNA), which is replaced by U5 and U6 snRNA. Here we use crosslinking to investigate snRNA interactions with the 5′ exon adjacent to the 5′ splice site, prior to the first step of splici...

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Bibliografiske detaljer
Main Authors: McGrail, Joanne C., O’Keefe, Raymond T.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2008
Fag:
RNA
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2241886/
https://ncbi.nlm.nih.gov/pubmed/18084028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm1098
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