Synergy between an antiangiogenic integrin α(v) antagonist and an antibody–cytokine fusion protein eradicates spontaneous tumor metastases

The suppression and eradication of primary tumors and distant metastases is a major goal of alternative treatment strategies for cancer, such as inhibition of angiogenesis and targeted immunotherapy. We report here a synergy between two novel monotherapies directed against vascular and tumor compart...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Lode, Holger N., Moehler, Thomas, Xiang, Rong, Jonczyk, Alfred, Gillies, Stephen D., Cheresh, David A., Reisfeld, Ralph A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15528/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9990069/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.4.1591
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