Molecular Fossils in the Human Genome: Identification and Analysis of the Pseudogenes in Chromosomes 21 and 22

We have developed an initial approach for annotating and surveying pseudogenes in the human genome. We search human genomic DNA for regions that are similar to known protein sequences and contain obvious disablements (i.e., mid-sequence stop codons or frameshifts), while ensuring minimal overlap wit...

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Bibliografiske detaljer

Udgivet i:	Genome Res
Principais autores:	Harrison, Paul M., Hegyi, Hedi, Balasubramanian, Suganthi, Luscombe, Nicholas M., Bertone, Paul, Echols, Nathaniel, Johnson, Ted, Gerstein, Mark
Format:	Artigo
Sprog:	Inglês
Udgivet:	Cold Spring Harbor Laboratory Press 2002
Fag:	Letter
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC155275/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11827946/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gr.207102
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