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Molecular Fossils in the Human Genome: Identification and Analysis of the Pseudogenes in Chromosomes 21 and 22

We have developed an initial approach for annotating and surveying pseudogenes in the human genome. We search human genomic DNA for regions that are similar to known protein sequences and contain obvious disablements (i.e., mid-sequence stop codons or frameshifts), while ensuring minimal overlap wit...

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Detalhes bibliográficos
Publicado no:Genome Res
Principais autores: Harrison, Paul M., Hegyi, Hedi, Balasubramanian, Suganthi, Luscombe, Nicholas M., Bertone, Paul, Echols, Nathaniel, Johnson, Ted, Gerstein, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC155275/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11827946/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gr.207102
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