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Rapid nanopore discrimination between single polynucleotide molecules

A variety of different DNA polymers were electrophoretically driven through the nanopore of an α-hemolysin channel in a lipid bilayer. Single-channel recording of the translocation duration and current flow during traversal of individual polynucleotides yielded a unique pattern of events for each of...

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Bibliografiska uppgifter
Huvudupphovsmän: Meller, Amit, Nivon, Lucas, Brandin, Eric, Golovchenko, Jene, Branton, Daniel
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 2000
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC15527/
https://ncbi.nlm.nih.gov/pubmed/10655487
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