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Quantify single nucleotide polymorphism (SNP) ratio in pooled DNA based on normalized fluorescence real-time PCR

BACKGROUND: Conventional real-time PCR to quantify the allele ratio in pooled DNA mainly depends on PCR amplification efficiency determination and Ct value, which is defined as the PCR cycle number at which the fluorescence emission exceeds the fixed threshold. Because of the nature of exponential c...

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Bibliographic Details
Main Authors: Yu, Airong, Geng, Haifeng, Zhou, Xuerui
Format: Artigo
Language:Inglês
Published: BioMed Central 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1552069/
https://ncbi.nlm.nih.gov/pubmed/16764712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-7-143
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