Stabilization of a Full-Length Infectious cDNA Clone of Transmissible Gastroenteritis Coronavirus by Insertion of an Intron

The stable propagation of a full-length transmissible gastroenteritis coronavirus (TGEV) cDNA in Escherichia coli cells as a bacterial artificial chromosome has been considerably improved by the insertion of an intron to disrupt a toxic region identified in the viral genome. The viral RNA was expres...

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Detalles Bibliográficos

Publicado en:	J Virol
Autores principales:	González, José M., Pénzes, Zoltan, Almazán, Fernando, Calvo, Enrique, Enjuanes, Luis
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 2002
Materias:	Replication
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC155106/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11932433/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.9.4655-4661.2002
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