CBP/p300 interact with and function as transcriptional coactivators of BRCA1

BRCA1 is a breast and ovarian cancer-specific tumor suppressor, with properties of a transcription factor involved in DNA repair. We previously have shown the transactivation of heterologous promoters by the carboxyl terminus of BRCA1. We now describe that BRCA1-mediated transactivation is enhanced...

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Main Authors: Pao, Gerald M., Janknecht, Ralf, Ruffner, Heinz, Hunter, Tony, Verma, Inder M.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2000
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC15508/
https://ncbi.nlm.nih.gov/pubmed/10655477
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