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Effective countermeasure against poisoning by organophosphorus insecticides and nerve agents

The nerve agents soman, sarin, VX, and tabun are deadly organophosphorus (OP) compounds chemically related to OP insecticides. Most of their acute toxicity results from the irreversible inhibition of acetylcholinesterase (AChE), the enzyme that inactivates the neurotransmitter acetylcholine. The lim...

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Main Authors: Albuquerque, Edson X., Pereira, Edna F. R., Aracava, Yasco, Fawcett, William P., Oliveira, Maristela, Randall, William R., Hamilton, Tracey A., Kan, Robert K., Romano, James A., Adler, Michael
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1550772/
https://ncbi.nlm.nih.gov/pubmed/16914529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605370103
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