Effective countermeasure against poisoning by organophosphorus insecticides and nerve agents

The nerve agents soman, sarin, VX, and tabun are deadly organophosphorus (OP) compounds chemically related to OP insecticides. Most of their acute toxicity results from the irreversible inhibition of acetylcholinesterase (AChE), the enzyme that inactivates the neurotransmitter acetylcholine. The lim...

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Bibliographic Details
Main Authors: Albuquerque, Edson X., Pereira, Edna F. R., Aracava, Yasco, Fawcett, William P., Oliveira, Maristela, Randall, William R., Hamilton, Tracey A., Kan, Robert K., Romano, James A., Adler, Michael
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2006
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1550772/
https://ncbi.nlm.nih.gov/pubmed/16914529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605370103
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