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Effective countermeasure against poisoning by organophosphorus insecticides and nerve agents

The nerve agents soman, sarin, VX, and tabun are deadly organophosphorus (OP) compounds chemically related to OP insecticides. Most of their acute toxicity results from the irreversible inhibition of acetylcholinesterase (AChE), the enzyme that inactivates the neurotransmitter acetylcholine. The lim...

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Detalhes bibliográficos
Main Authors: Albuquerque, Edson X., Pereira, Edna F. R., Aracava, Yasco, Fawcett, William P., Oliveira, Maristela, Randall, William R., Hamilton, Tracey A., Kan, Robert K., Romano, James A., Adler, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1550772/
https://ncbi.nlm.nih.gov/pubmed/16914529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605370103
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