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Effective countermeasure against poisoning by organophosphorus insecticides and nerve agents

The nerve agents soman, sarin, VX, and tabun are deadly organophosphorus (OP) compounds chemically related to OP insecticides. Most of their acute toxicity results from the irreversible inhibition of acetylcholinesterase (AChE), the enzyme that inactivates the neurotransmitter acetylcholine. The lim...

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Bibliografiske detaljer
Main Authors: Albuquerque, Edson X., Pereira, Edna F. R., Aracava, Yasco, Fawcett, William P., Oliveira, Maristela, Randall, William R., Hamilton, Tracey A., Kan, Robert K., Romano, James A., Adler, Michael
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1550772/
https://ncbi.nlm.nih.gov/pubmed/16914529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605370103
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