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Adeno-Associated Virus Capsids Displaying Immunoglobulin-Binding Domains Permit Antibody-Mediated Vector Retargeting to Specific Cell Surface Receptors

Recombinant adeno-associated virus type 2 (rAAV2) is a promising vector for human somatic gene therapy. However, its broad host range is a disadvantage for some applications, because it reduces the specificity of the gene transfer. To overcome this limitation, we sought to create a versatile rAAV ve...

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Bibliografische gegevens
Hoofdauteurs: Ried, Martin U., Girod, Anne, Leike, Kristin, Büning, Hildegard, Hallek, Michael
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2002
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC155067/
https://ncbi.nlm.nih.gov/pubmed/11932421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.9.4559-4566.2002
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