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CD137 costimulatory T cell receptor engagement reverses acute disease in lupus-prone NZB × NZW F(1) mice

Systemic lupus erythematosus (SLE) is a CD4(+) T cell–dependent, immune complex–mediated, autoimmune disease that primarily affects women of childbearing age. Generation of high-titer affinity-matured IgG autoantibodies, specific for double-stranded DNA and other nuclear antigens, coincides with dis...

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Yayımlandı:J Clin Invest
Asıl Yazarlar: Foell, Juergen, Strahotin, Simona, O’Neil, Shawn P., McCausland, Megan M., Suwyn, Carolyn, Haber, Michael, Chander, Praveen N., Bapat, Abhijit S., Yan, Xiao-Jie, Chiorazzi, Nicholas, Hoffmann, Michael K., Mittler, Robert S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2003
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC155050/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12750400/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI17662
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