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Vpr R77Q is associated with long-term nonprogressive HIV infection and impaired induction of apoptosis

The absence of immune defects that occurs in the syndrome of long-term nonprogressive (LTNP) HIV infection offers insights into the pathophysiology of HIV-induced immune disease. The (H[F/S]RIG)(2) domain of viral protein R (Vpr) induces apoptosis and may contribute to HIV-induced T cell depletion....

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Main Authors:	Lum, Julian J., Cohen, Oren J., Nie, Zilin, Weaver, Joel G., Gomez, Timothy S., Yao, Xiao-Jian, Lynch, David, Pilon, André A., Hawley, Nanci, Kim, John E., Chen, Zhaoxia, Montpetit, Michael, Sanchez-Dardon, Jaime, Cohen, Eric A., Badley, Andrew D.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Clinical Investigation 2003
נושאים:	Article
גישה מקוונת:	https://ncbi.nlm.nih.gov/pmc/articles/PMC155040/ https://ncbi.nlm.nih.gov/pubmed/12750404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200316233
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Vpr R77Q is associated with long-term nonprogressive HIV infection and impaired induction of apoptosis

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